THE ACQUISITION OF HOST-ENCODED PROTEINS BY NASCENT HIV-I

The human immunodeficiency virus type 1 (HIV-1) incorporates several h ost-derived proteins during the budding process. Here, Michel Tremblay and colleagues review recent studies that indicate that virion-bound host molecules are still functional and are affecting the biological p roperties of HIV-1. Therefore, these nonviral components should be con sidered as factors putatively affecting the pathogenesis of HIV-1 infe ction.