Fibrinolytic therapy for acute myocardial infarction, even with the mo
st efficient regimens available, is fraught with a substantial proport
ion of failures to reopen the occluded vessel. The term rescue percuta
neous transluminal coronary angioplasty (PTCA) has been introduced to
describe an attempt to mechanically recanalize the infarct vessel if f
ibrinolytic reperfusion fails. Despite the intuitive appeal and widesp
read use of rescue PTCA, only a limited amount of data (mostly observa
tional retrospective data) is available to confirm the clinical benefi
t of this therapeutic option.