HENOCH-SCHONLEIN PURPURA - A REVIEW

Henoch-Schonlein purpura is an IgA-mediated, autoimmune, hypersensitiv ity vasculitis of childhood that results in a triad of symptoms, inclu ding a purpuric rash occurring on the lower extremities, abdominal pai n or renal involvement, and arthritis. However, any of the triad may b e absent, which often leads to confusion in diagnosing the condition. Although the cause is unknown, Henoch-Schonlein purpura is often assoc iated with infectious agents such as group A streptococci and Mycoplas ma. It has also been associated with food reactions, exposure to cold, insect bites and drug allergies. Treatment is supportive, and childre n affected by this disorder need close follow-up of renal status.