Obesity, diabetes mellitus, and hypertension are common, interrelated
medical problems in Westernized, industrialized societies. These inter
related medical conditions are associated with an increased risk of ca
rdiovascular disease and are more prevalent in several minority groups
, including African-American and Hispanic populations. The associated
cardiovascular risks of these problems are more thoroughly addressed i
n another review in this supplement. Obesity markedly enhances the dev
elopment of Type 2 diabetes. Moreover, it enhances the cardiovascular
risk associated with other risk factors, such as hypertension and dysl
ipidemia. Weight reduction in association with an aerobic exercise pro
gram improves metabolic abnormalities and reduces blood pressure in in
dividuals with diabetes and hypertension.