LIPASE-CATALYZED RESOLUTION OF STEREOGENIC CENTERS IN STEROID SIDE-CHAINS BY TRANSESTERIFICATION IN ORGANIC-SOLVENTS - THE CASE OF A 26-HYDROXYCHOLESTEROL

Authors
FERRABOSCHI P REZAELAHI S VERZA E SANTANIELLO E
Citation
P. Ferraboschi et al., LIPASE-CATALYZED RESOLUTION OF STEREOGENIC CENTERS IN STEROID SIDE-CHAINS BY TRANSESTERIFICATION IN ORGANIC-SOLVENTS - THE CASE OF A 26-HYDROXYCHOLESTEROL, Tetrahedron : asymmetry, 9(13), 1998, pp. 2193-2196
Citations number
22
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
9
Issue
13
Year of publication
1998
Pages
2193 - 2196
Database
ISI
SICI code
0957-4166(1998)9:13<2193:LROSCI>2.0.ZU;2-V
Abstract
The Pseudomonas cepacia (PCL) lipase selectively catalyzes the acylati on of the (25S)-isomer of the (25R,S)-26-hydroxycholesterol la when th e transesterification is irreversibly carried out with vinyl acetate i n a mixture of organic solvents (chloroform/tetrahydrofuran). (C) 1998 Elsevier Science Ltd. All rights reserved.