ASYMMETRIZATION OF MESO-1,3-DIOLS UTILIZING PSEUDOMONAS-FLUORESCENS LIPASE

Authors
ALEXANDRE FR HUET F
Citation
Fr. Alexandre et F. Huet, ASYMMETRIZATION OF MESO-1,3-DIOLS UTILIZING PSEUDOMONAS-FLUORESCENS LIPASE, Tetrahedron : asymmetry, 9(13), 1998, pp. 2301-2310
Citations number
15
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
9
Issue
13
Year of publication
1998
Pages
2301 - 2310
Database
ISI
SICI code
0957-4166(1998)9:13<2301:AOMUPL>2.0.ZU;2-F
Abstract
A convenient and enantioselective synthesis of monoacetates of meso-1, 3-diols 2-substituted with an alkoxymethyl or a thiophenylmethyl group , by enzyme catalyzed acylation, is described. The absolute stereochem istries of two monoacetates were assigned by chemical correlation. (C) 1998 Elsevier Science Ltd. All rights reserved.