ASYMMETRIC-SYNTHESIS OF (2S,3R,4R)-ETHOXYCARBONYLCYCLOPROPYL PHOSPHONOGLYCINE

Authors
HANNOUR S ROUMESTANT ML VIALLEFONT P RICHE C MARTINEZ J ELHALLAOUI A OUAZZANI F
Citation
S. Hannour et al., ASYMMETRIC-SYNTHESIS OF (2S,3R,4R)-ETHOXYCARBONYLCYCLOPROPYL PHOSPHONOGLYCINE, Tetrahedron : asymmetry, 9(13), 1998, pp. 2329-2332
Citations number
9
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
9
Issue
13
Year of publication
1998
Pages
2329 - 2332
Database
ISI
SICI code
0957-4166(1998)9:13<2329:AO(P>2.0.ZU;2-G
Abstract
The synthesis of enantiomeric ally pure (2S, 3R,4R)-ethoxycarbonylcycl opropyl phosphonoglycine is described, the key-step involving 1,4-addi tion of a chiral enolate to ethyl 4-bromo-crotonate. (C) 1998 Elsevier Science Ltd. All rights reserved.