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ITA
ENG
HIV-1 PROTEASE INHIBITORS BASED ON ACYCLIC CARBOHYDRATES
Authors
ZUCCARELLO G
BOUZIDE A
KVARNSTROM I
NIKLASSON G
SVENSSON SCT
BRISANDER M
DANIELSSON H
NILLROTH U
KARLEN A
HALLBERG A
CLASSON B
SAMUELSSON B
Citation
G. Zuccarello et al., HIV-1 PROTEASE INHIBITORS BASED ON ACYCLIC CARBOHYDRATES, Journal of organic chemistry, 63(15), 1998, pp. 4898-4906
Citations number
52
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of organic chemistry
→
ACNP
ISSN journal
00223263
Volume
63
Issue
15
Year of publication
1998
Pages
4898 - 4906
Database
ISI
SICI code
0022-3263(1998)63:15<4898:HPIBOA>2.0.ZU;2-6
Abstract
A series of acyclic Ct-symmetric HIV protease inhibitors readily acces sible from D-mannitol have been developed. Several of the compounds sy nthesized showed significant in vitro activity against HIV-1 protease.