Jb. Parkhurst et al., UPSTAGING OF NON-HODGKINS-LYMPHOMA IN A CHILD BASED ON (67)GALLIUM SCINTIGRAPHY, Journal of pediatric hematology/oncology, 20(2), 1998, pp. 174-176
Purpose: To describe a patient whose non-Hodgkin's lymphoma (NHL) appe
ared to be localized by standard modalities but who was upstaged after
Gallium scintigraphy suggested disseminated disease. Patient and Meth
ods: A patient with biopsy proven NHL in the maxillary sinus was stage
d as having localized disease based on computed tomography (CT) scans,
bone scintigraphy, and evaluation of bone marrow and spinal fluid. Op
en biopsy of a bony lesion, standard modalities for lymphoma staging,
and Gallium scintigraphy were obtained. Results: Gallium scanning show
ed bony lesions not previously seen with the standard modalities. Open
biopsy of one of these lesions confirmed disseminated disease. Conclu
sions: Gallium scanning aids in the early identification of metastases
in some patients with NHL and should be included in a standard evalua
tion of apparently localized disease.