PREPARATION AND CHARACTERIZATION OF WATER-SOLUBLE CHITIN AND CHITOSANDERIVATIVES

Authors
SUGIMOTO M MORIMOTO M SASHIWA H SAIMOTO H SHIGEMASA Y
Citation
M. Sugimoto et al., PREPARATION AND CHARACTERIZATION OF WATER-SOLUBLE CHITIN AND CHITOSANDERIVATIVES, Carbohydrate polymers, 36(1), 1998, pp. 49-59
Citations number
23
Categorie Soggetti
Chemistry Applied","Chemistry Inorganic & Nuclear","Polymer Sciences
Journal title
Carbohydrate polymers → ACNP
ISSN journal
01448617
Volume
36
Issue
1
Year of publication
1998
Pages
49 - 59
Database
ISI
SICI code
0144-8617(1998)36:1<49:PACOWC>2.0.ZU;2-W
Abstract
Chitosan was modified with poly(ethylene glycol)-aldehyde (PEG-aldehyd e) of various molecular weights under the various molar ratios of PEG- aldehyde to chitosan. Then the prepared chitosan-PEG hybrid was conver ted to chitin-PEG hybrid by the acetylation with acetic anhydride. The solubility of various derivatives was investigated in three buffers o f various pH. Some of these derivatives were soluble in 0.01 M phospha te buffer saline (PBS, pH = 7.2). The solubility in PBS was dependent on the degree of PEG substitution, the degree of acetylation, the mole cular weight of PEG, and the weight ratio of PEG in chitin/chitosan-PE G hybrid. (C) 1998 Elsevier Science Ltd. All rights reserved.