SURFACE AMINATION OF PEEK FILM BY SELECTIVE WET-CHEMISTRY

Using 4,4'-dimethoxybenzhydrol as soluble mimic of the reduced poly(ar yl ether ether ketone) (PEEK) monomer unit, we established the best ex perimental conditions to replace the hydroxyl group with an amine func tion, on the one hand, and to fix an amino acid residue, on the other hand. The selected strategies were then adapted to the surface functio nalization of the PEEK-OH film obtained by reduction of the PEEK precu rsor. Thus, reaction with phenylcarbamate followed by LiOH hydrolysis gave the PEEK-NH2 film characterized by theta(w), multiple internal re flection (MIR) and X-ray photoelectron specstroscopy, (XPS). The PEEK- NH2 was further derivatized with 1,3-propanesultone. Reaction of PEEK- OH with N'-(9-fluorenylmethoxvcarbonyl) (L) glutamine followed by pipe ridine deprotection gave the PEEK-glutamine sim characterized by theta (w), MIR and XPS. (C) 1998 Published by Elsevier Science Ltd. All righ ts reserved.