SYNTHESES OF FUNCTIONALIZED POLYMETHACRYLAMIDES BASED ON METHIONINE OXIDES

Radical polymerizations of methacrylamides having methionine, methioni ne sulfoxide, and methionine sulfone moieties, and oxidations of the p olymethacrylamide having a methionine moiety were examined. The radica l polymerizations of the monomers were carried out using 2,2'-azobis(i sobutyronitrile) (AIBN) as an initiator to afford the corresponding po lymers in good yields. The polymer with a methionine structure was oxi dized by 2 and 10 equivalents of hydrogen peroxide to obtain polymers having methionine sulfoxide and sulfone structures in the side chains, respectively. (C) 1998 Elsevier Science Ltd. All rights reserved.