3,4-DIMETHYLINDOLE-2-CARBOXYLATE AND 4-(1-HYDROXYETHYL)QUINOLINE-2-CARBOXYLATE ACTIVATING ENZYMES FROM THE NOSIHEPTIDE AND THIOSTREPTON PRODUCERS, STREPTOMYCES-ACTUOSUS AND STREPTOMYCES-LAURENTII
Tm. Smith et al., 3,4-DIMETHYLINDOLE-2-CARBOXYLATE AND 4-(1-HYDROXYETHYL)QUINOLINE-2-CARBOXYLATE ACTIVATING ENZYMES FROM THE NOSIHEPTIDE AND THIOSTREPTON PRODUCERS, STREPTOMYCES-ACTUOSUS AND STREPTOMYCES-LAURENTII, Journal of the Chemical Society, Chemical Communications, (21), 1993, pp. 1612-1614
Highly specific enzymes which activate 3,4-dimethylindole-2-carboxylat
e (DMI) and 4-(1-hydroxyethyl)quinoline-2-carboxylate (HEQ) to their a
cyl adenylates have been detected in cell-free extracts of the nosihep
tide and thiostrepton producers, S. actuosus and S. laurentii, by an A
TP/PP(i) exchange assay.