KINETIC RESOLUTION OF THE CHIRAL IRON ACETYL [FE(MU(5)-C5H5)(CO)(PPH3)COME]

Authors
CASEGREEN SC COSTELLO JF DAVIES SG HEATON N HEDGECOCK CJR PRIME JC
Citation
Sc. Casegreen et al., KINETIC RESOLUTION OF THE CHIRAL IRON ACETYL [FE(MU(5)-C5H5)(CO)(PPH3)COME], Journal of the Chemical Society, Chemical Communications, (21), 1993, pp. 1621-1622
Citations number
15
Categorie Soggetti
Chemistry
Journal title
Journal of the Chemical Society, Chemical Communications → ACNP
ISSN journal
00224936
Issue
21
Year of publication
1993
Pages
1621 - 1622
Database
ISI
SICI code
0022-4936(1993):21<1621:KROTCI>2.0.ZU;2-7
Abstract
The chiral discrimination displayed between the enolate derived from ( RS)-[Fe(eta5-C5H5)(CO)(PPh3)COMe] and (1R)-(+)-camphor furnishes a pra ctical route to homochiral (R)-[Fe(eta5-C5H5)(CO)(PPh3)COMe] Via a kin etic resolution protocol, while a retro-aldol reaction of the diastere oisomerically pure aldol addition product of this kinetic resolution s equence provides a complementary route to the opposite enantiomer (S)- [Fe(eta5-C5H5)(CO)(PPh3)COMe].