The purpose of this review is to describe recent advances in non-invas
ive vascular imaging techniques and to discuss their current clinical
applications for imaging of peripheral vessels. Principles for applyin
g ultrasound, CT angiography (CTA), and magnetic resonance angiography
(MRA) for non-invasive imaging of peripheral arteries and veins are p
resented. Clinical applications are reviewed for different vascular di
seases, therapy planning, and follow-up studies. Conventional Doppler
and color duplex sonography are the most cost-effective procedures to
detect or rule out peripheral arterial occlusive disease (PAOD) and to
provide specific recommendations for therapy. In the near future, con
trast-enhanced MRA (CE MRA) with additional axial two-dimensional time
-of-flight studies to search for non-anatomic runoff will replace diag
nostic intra-arterial digital subtraction angiography (DSA) for planni
ng of reconstructive surgery with acquisition slabs displaying project
ions similar to intra-arterial DSA. Color duplex sonography should als
o be the first non-invasive technique applied for the detection of per
ipheral aneurysms. Preoperative or preinterventional therapy planning
of aneurysms may be performed by CTA or CE MRA. Compression ultrasound
is the imaging procedure of choice in deep venous thrombosis (DVT). I
n the preoperative assessment of venous incompetence, color duplex son
ography is the imaging technique which is sufficient in most cases.