Wernicke's encephalopathy is an uncommon disorder caused by a thiamine
deficiency which is clinically characterized by the triad of ophthalm
oplegia, ataxia and disturbances of consciousness, each finding being
variably present. The disease is caused by malnutrition or malabsorpti
on, and is often associated with prolonged alcohol intake, neoplasm an
d extensive inflammatory processes of the digestive tract and parenter
al hyperalimentation-induced gastrointestinal mucosal atrophy. Clinica
l diagnosis can be elusive and MRI may be the only imaging technique a
ble to detect the cerebral lesions, whose type and distribution are ch
aracteristic of the Wernicke's encephalopathy, whereas CT is positive
only in exceptional cases. We report a case of a 56-year-old woman who
developed a Wernicke's encephalopathy 1 month after a colonic resecti
on with signal intensify changes located in the mammillary bodies and
in the medial thalamic nuclei.