J. Matsui et al., DESIGN AND PREPARATION OF MOLECULARLY IMPRINTED ATRAZINE-RECEPTOR POLYMERS - INVESTIGATION OF FUNCTIONAL MONOMERS AND SOLVENTS, Analytical sciences, 14(4), 1998, pp. 699-702
The preparation of atrazine-receptor polymers by molecular imprinting
was explored, focusing upon the role of functional monomer and solvent
used for the preparation. Three functional monomers and six different
solvents were examined from the viewpoint of the efficiency for molec
ular imprinting. Polymers were prepared using methacrylic acid, a stro
nger acid 2-(trifluoromethyl)acrylic acid and a three-point hydrogen b
ond donor/acceptor, glutethimide derivative. Methacrylic acid displaye
d the best effectiveness as functional monomer, which leads to an unde
rstanding that a functional monomer is required to have both strong bi
nding and multiple binding capacity. By choosing less polar solvents f
or polymerization, polymers having better retention ability and higher
selectivity were obtained. Those polymers exhibited capacity factors
2 - 2.5 times as large as that for chloroform. Is was also suggested t
hat the molecular shape and size of the solvent used have influence on
the resultant polymer's binding ability.