The aim of this study was to assess the prevalence of ataxia of stance
in different types of alcohol-dependent patients. Posturographic meas
urements were performed in 82 abstinent alcohol-dependent patients and
54 healthy controls in order to analyse postural control. According t
o Lesch and co-workers, alcohol dependence was classified as total abs
tinence (Type I), drinking without loss of control (Type II), fluctuat
ing course (Type III), and persistent severe drinking (Type IV). The m
echanisms of alcohol dependence in these subtypes can be summarized as
follows: Type 1 patients drink alcohol to counteract symptoms of alco
hol withdrawal; Type II patients use alcohol as an agent for solving c
onflicts; Type III patients drink alcohol to 'treat' an affective diso
rder; and Type IV patients have a history of pre-alcoholic neurologica
l and/or psychiatric disorders. The neurological examination showed pa
thological findings in 39%, whereas posturographic measurements uncove
red impaired postural control in 61% (chi(2) = 8.8, P = 0.003). Compar
ing the different study groups revealed that ataxia of stance was most
common in alcohol-dependent patients classified as Type IV (tau = 0.2
4, P = 0.005). In conclusion, posturographic measurements are superior
to the clinical examination in detecting postural imbalance in alcoho
l-dependent patients. The prevalence of postural imbalance is highest
in patients classified by Lesch as Type IV. Consequently, this type of
alcohol dependence - characterized by pre-alcoholic neurological and/
or psychiatric disorders, bears the highest risk of developing ataxia
of stance.