GIANT-CELL TUMOR OF THE LARYNX

Among the more uncommon tumors that may sometimes be encountered in th e laryngeal region is the recently described giant cell tumor of the l arynx. This lesion is a true neoplasm, presumably of the fibrohistiocy tic series. Histologically, it closely resembles the more familiar tru e giant cell tumor of long bone. The laryngeal giant cell tumors appea r, to date, to be nonmetastasizing lesions; it is possible that they m ay recur locally if incompletely excised (although this remains to be demonstrated). In view of the rarity of these tumors, a tentative diag nosis of such a neoplasm should always prompt consideration of other ( more frequently encountered) differential diagnostic possibilities, in cluding cytologically malignant giant cell-rich tumors such as maligna nt fibrous histiocytoma and sarcomatoid carcinoma.