Two new scalarane derivatives, phyllactones F and G, have been isolate
d from the sponge Phyllospongia foliascens. Compounds 1 and 2 are anom
ers whose structures were determined on the basis of spectral data. Th
e absolute stereochemistry of phyllactone B [6] has been established u
sing Mosher's method, and this permitted verification of the assignmen
ts of absolute stereochemistry for all scalarane sesterterpenes isolat
ed from the Chinese sponge P. foliascens.