Mr. Clarke et S. Boppana, HEMANGIOMA OF THE THYROID-GLAND IN AN ADOLESCENT WITH CHRONIC LYMPHOCYTIC THYROIDITIS AND ADENOMATOUS HYPERPLASIA, Endocrine pathology, 9(2), 1998, pp. 185-189
We report a case of benign hemangioma of the thyroid gland which invol
ved one lobe of the thyroid gland in an adolescent female with classic
chronic lymphocytic thyroiditis and adenomatous hyperplasia. The lesi
on produced a clinical picture suspicious for malignancy owing to the
presence of a very large cold nodule on scan, lack of response to TSH
suppression, and the subsequent development of an enlarged cervical ly
mph node. The histologic and immunohistologic findings, including posi
tive staining for factor VIII-related antigen, Ulex europaeous lectin,
CD31, CD34, and the presence of linear staining for type IV collagen
and laminin are consistent with a hemangioma. In our review of the lit
erature, only one other report of a hemangioma of the thyroid gland wa
s found.