E. Vestergren et al., ADMINISTERED ACTIVITY OF TC-99(M)-DMSA FOR KIDNEY SCINTIGRAPHY IN CHILDREN, Nuclear medicine communications, 19(7), 1998, pp. 695-701
Kidney scintigraphy using Tc-99(m)-dimercaptosuccinic acid (DMSA) is a
common gamma camera investigation in paediatric patients The present
study deals with methods of calculating the activity to be administere
d to children. Our aim is to find a method of calculation which gives
the same count density in the gamma camera images for all ages. Four d
ifferent methods, based on body weight, height, body surface area and
a theoretical model, are compared. The count density in the images of
the kidneys was studied retrospectively in 85 patients aged between 3
weeks and 19.5 years. Fourteen young adults aged 22.0-31.9 years were
also studied. Two of the calculation methods, based on body surface ar
ea and the theoretical model, showed no apparent age dependency (i.e.
a constant count density was observed for all ages). The variation bet
ween individuals was similar with both methods, but only the body surf
ace area method gave a count density comparable to that for the young
adults. As the method based on body surface area is also easy to imple
ment, this method is recommended. ((C) 1998 Lippincott-Raven Publisher
s).