FIBROSARCOMA FOLLOWING RADIOTHERAPY FOR BREAST-CARCINOMA - A CASE-REPORT AND REVIEW OF THE LITERATURE

The 17 patients with fibrosarcoma occurring after radiotherapy for bre ast carcinoma reported in the literature are the disastrous results of a treatment modality. All the reports concerning the sarcomas share t he same feature-aggressive nature with a latent period of 4 years or m ore. A patient report of fibrosarcoma occurring 2 years after radiothe rapy for breast carcinoma with the shortest latent period in the liter ature is presented and the literature is reviewed. The tumor was local ized within an irradiated area and there was a clear histological dist inction between the previous and current tumors, The tumor was found t o encase the axillary artery and the brachial plexus, For a curative r esection, a forequarter amputation was performed and the defect was cl osed by means of a posterior arm flap. Despite the aggressiveness of t he tumors the patient had no distant metastases 1 year after the diagn osis of fibrosarcoma.