Objective: Blood transfusion raises serious issues of safety and econo
mics. We therefore examined blood usage and its characteristics in med
ical inpatients, given the relative scarcity of existing data. Design:
During a 1-year period, transfusion episodes on two medical services
were reviewed by five specialists for justifiability on the basis of g
enerally agreed on guidelines. Setting: The study was conducted at two
institutions, a municipal teaching hospital where house staff deliver
care and a community hospital where patients are under the direct car
e of private physicians. Patients: Four hundred thirty-eight randomly
selected transfusion episodes on the medical services of the two insti
tutions were reviewed. Main Outcome Measures: The prevalence of unjust
ifiable transfusions based only on the information available to the ma
naging physician at the time of transfusion. Results: Eighteen percent
of the 438 randomly selected transfusion episodes were viewed as not
justifiable by at least four of five reviewers; another 17% were class
ified as equivocal because two or three reviewers judged them to be no
t justifiable. The most striking observation was the greater prevalenc
e of nonjustifiable transfusion episodes at the community hospital (26
% vs 16% at the teaching institution; P=.0121). Other observations inc
luded a tendency for physicians to prescribe transfusions by the numbe
rs (at least 11% of nonjustifiable transfusions) and to overtransfuse.
The routineness with which transfusion was viewed by managing physici
ans was also identifiable by the absence of written transfusion notes
in 39% of all episodes reviewed, which incidentally raises questions a
bout the adequacy of the medical chart's documentary functions today.
Conclusions: The rate of nonjustifiable or equivocal transfusion on me
dical services may be as high as 35%. Reliance on numbers rather than
clinical status seems to be a major problem. Education is obviously a
critical issue and should also target private practitioners, who seeme
d to perform less well than physicians in training. Transfusion guidel
ines that use specific hematocrit values also need to be reexamined.