Mw. Ding et al., SYNTHESIS AND BIOLOGICAL-ACTIVITIES OF NOVEL 2-AMINO-5-BENZYLIDENE-4H-IMIDAZOLIN-4-ONE DERIVATIVES, Gaodeng xuexiao huaxue xuebao, 19(6), 1998, pp. 895-898
The carbodiimide 2, which was obtained from aza-Wittig reaction of vin
yliminophosphorane with aromatic isocyanate, reacted with nucleophiles
to give ten novel 2-amino-5-benzylidene-4H-imidazolin-4-one derivativ
es. The reactivity of carbodiimide 2 towards various nucleophiles was
studied and a gualidene-like intermediate 3i was isolated from the rea
ction mixture, Preliminary evaluation of the biological activities of
compound 4 was made.