SYNTHESIS AND BIOLOGICAL-ACTIVITIES OF NOVEL 2-AMINO-5-BENZYLIDENE-4H-IMIDAZOLIN-4-ONE DERIVATIVES

Authors
DING MW TU HY LIU ZJ ZHUANG NB
Citation
Mw. Ding et al., SYNTHESIS AND BIOLOGICAL-ACTIVITIES OF NOVEL 2-AMINO-5-BENZYLIDENE-4H-IMIDAZOLIN-4-ONE DERIVATIVES, Gaodeng xuexiao huaxue xuebao, 19(6), 1998, pp. 895-898
Citations number
10
Categorie Soggetti
Chemistry
Journal title
Gaodeng xuexiao huaxue xuebao → ACNP
ISSN journal
02510790
Volume
19
Issue
6
Year of publication
1998
Pages
895 - 898
Database
ISI
SICI code
0251-0790(1998)19:6<895:SABON2>2.0.ZU;2-O
Abstract
The carbodiimide 2, which was obtained from aza-Wittig reaction of vin yliminophosphorane with aromatic isocyanate, reacted with nucleophiles to give ten novel 2-amino-5-benzylidene-4H-imidazolin-4-one derivativ es. The reactivity of carbodiimide 2 towards various nucleophiles was studied and a gualidene-like intermediate 3i was isolated from the rea ction mixture, Preliminary evaluation of the biological activities of compound 4 was made.