M. Portolani et al., EPSTEIN-BARR-VIRUS DNA IN CEREBROSPINAL-FLUID FROM AN IMMUNOCOMPETENTMAN WITH HERPES-SIMPLEX VIRUS ENCEPHALITIS, Journal of neurovirology, 4(4), 1998, pp. 461-464
Herpes simplex virus 1 meningo-encephalitis was ascertained in a 63-ye
ar-old immunocompetent man. To determine the duration of the persisten
ce of herpesvirus DNA in the central nervous system, the cerebrospinal
fluid was periodically monitored by polymerase chain reaction for 53
days. In addition to HSV-1, Epstein - Barr virus DNA was detected in t
he cerebrospinal fluid 9 days after disease onset. The possible meanin
g of the Epstein-Barr virus DNA finding is discussed.