SYNTHESIS OF THE TRIFLUOROACETATE SALT OF ASPARTIC-ACID BETA-SEMIALDEHYDE, AN INTERMEDIATE IN THE BIOSYNTHESIS OF L-LYSINE, L-THREONINE, AND L-METHIONINE

Authors
TUDOR DW LEWIS T ROBINS DJ
Citation
Dw. Tudor et al., SYNTHESIS OF THE TRIFLUOROACETATE SALT OF ASPARTIC-ACID BETA-SEMIALDEHYDE, AN INTERMEDIATE IN THE BIOSYNTHESIS OF L-LYSINE, L-THREONINE, AND L-METHIONINE, Synthesis, (11), 1993, pp. 1061-1062
Citations number
10
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthesis → ACNP
ISSN journal
00397881
Issue
11
Year of publication
1993
Pages
1061 - 1062
Database
ISI
SICI code
0039-7881(1993):11<1061:SOTTSO>2.0.ZU;2-Z
Abstract
The trifluoroacetate salt of aspartic acid beta-semialdehyde, an impor tant intermediate in the biosynthesis Of L-lysine, L-threonine, and L- methionine has been prepared in DL-, L-, and D-forms as stable solid h ydrates 13 in 43 % overall yield by ozonolysis of doubly protected all ylglycine, followed by careful deprotection with trifluoroacetic acid.