FACILE SYNTHESIS AND REACTIONS OF (Z)-ALPHA,BETA-DIDEHYDROAMINO ALDEHYDES FROM (Z)-ALPHA,BETA-DIDEHYDROAMINO ACID-ESTERS

Authors
NAKAMURA Y SHIN CG
Citation
Y. Nakamura et Cg. Shin, FACILE SYNTHESIS AND REACTIONS OF (Z)-ALPHA,BETA-DIDEHYDROAMINO ALDEHYDES FROM (Z)-ALPHA,BETA-DIDEHYDROAMINO ACID-ESTERS, Synthesis, (11), 1993, pp. 1158-1161
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthesis → ACNP
ISSN journal
00397881
Issue
11
Year of publication
1993
Pages
1158 - 1161
Database
ISI
SICI code
0039-7881(1993):11<1158:FSARO(>2.0.ZU;2-O
Abstract
The general synthesis of (Z)-alpha,beta-didehydroamino aldehydes 3 was accomplished by the reduction of (Z)-alpha,beta-didehydroamino acid e sters with lithium aluminum hydride followed by Swern oxidation. Subse quent Grignard reaction of 3 with alkylmagnesium halides was carried o ut to give various N-protected amino alkenols and amino alkadienols.