AN IN-SITU SYNTHESIS OF CYANOGEN CHLORIDE AS A SAFE AND ECONOMICAL AQUEOUS STANDARD

This study developed the in situ synthesis of CNCI as a Safe and econo mical aqueous standard, based on Standard Method 500-CN- E. This study demonstrated that the synthesized CNCI standards are comparable with commercial standards based on results from purge-and-trap GC/MS analys is and micro-liquid/liquid extraction with GC/ECD analysis. Furthermor e, the synthesized CNCI solution provides a source of externally prepa red standards, which avoids gas-liquid transfer procedures. Only micro gram quantities of this hazardous substance were generated and may be safely converted to the relatively innocuous cyanate ion immediately a fter use by simply raising the pH. This performance-based approach led to a successful means to synthesize aqueous CNCI solutions as either quality control standards or calibration standards. It may be especial ly useful for laboratories in other countries where CNCI is difficult to acquire. (C) 1998 Elsevier Science Ltd. All rights reserved.