RADIOLOGIC PROGRESSION IN PATIENTS WITH JUVENILE CHRONIC ARTHRITIS TREATED WITH METHOTREXATE

Authors
RAVELLI A VIOLA S RAMENGHI B BELUFFI G ZONTA LA MARTINI A
Citation
A. Ravelli et al., RADIOLOGIC PROGRESSION IN PATIENTS WITH JUVENILE CHRONIC ARTHRITIS TREATED WITH METHOTREXATE, The Journal of pediatrics, 133(2), 1998, pp. 262-265
Citations number
13
Categorie Soggetti
Pediatrics
Journal title
The Journal of pediatrics → ACNP
ISSN journal
00223476
Volume
133
Issue
2
Year of publication
1998
Pages
262 - 265
Database
ISI
SICI code
0022-3476(1998)133:2<262:RPIPWJ>2.0.ZU;2-L
Abstract
We investigated the rate of radiologic progression, as measured by car pal length, in 26 children with juvenile chronic arthritis who were tr eated with methotrexate. After 2 years of treatment, the carpal length was significantly more deteriorated in nonresponders in both the ''be tter'' wrist (P = .001) and the ''worse'' wrist (P = .005). These resu lts show that methotrexate may have a ''disease modifying'' potential in juvenile chronic arthritis.