COMBINED SCHEDULE OF 7-VALENT PNEUMOCOCCAL CONJUGATE VACCINE FOLLOWEDBY 23-VALENT PNEUMOCOCCAL VACCINE IN CHILDREN AND YOUNG-ADULTS WITH SICKLE-CELL DISEASE
L. Vernacchio et al., COMBINED SCHEDULE OF 7-VALENT PNEUMOCOCCAL CONJUGATE VACCINE FOLLOWEDBY 23-VALENT PNEUMOCOCCAL VACCINE IN CHILDREN AND YOUNG-ADULTS WITH SICKLE-CELL DISEASE, The Journal of pediatrics, 133(2), 1998, pp. 275-278
We compared the immunogenicity of 7-valent pneumococcal-conjugate vacc
ine plus 23-valent pneumococcal vaccine to immunization with 23-valent
vaccine only in individuals greater than or equal to 2 years of age w
ith sickle cell disease. IgG pneumococcal antibody concentrations were
higher in the combined schedule group with no increase in side effect
s observed after immunization with 23-valent vaccine.