SYNTHESIS OF 7,8,9-TETRAHYDRO-6H-PYRAZOLO[3,4-B]QUINOLIN-5-ONES

Authors
QUIROGA J INSUASTY B HORMAZA A SAITZ C JULLIAN C
Citation
J. Quiroga et al., SYNTHESIS OF 7,8,9-TETRAHYDRO-6H-PYRAZOLO[3,4-B]QUINOLIN-5-ONES, Journal of heterocyclic chemistry, 35(3), 1998, pp. 575-578
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of heterocyclic chemistry → ACNP
ISSN journal
0022152X
Volume
35
Issue
3
Year of publication
1998
Pages
575 - 578
Database
ISI
SICI code
0022-152X(1998)35:3<575:SO7>2.0.ZU;2-T
Abstract
Reaction of 5-amino-3-methyl-1-phenylpyrazole (1a) and 5-amino-3-(4-ch lorophenyl)-1H-pyrazole (1b) with dimedone (2) and p-susbstituted benz aldehydes 3 in ethanol, afforded in all cases tricyclic linear 4-aryl- 7,7-dimethyl-4,7,8,9-tetrahydro-6H-pyrazolo[3,4-b] quinolin-5-ones (4 a-j) in good yields. The linear structures and hence the regiospecific ity of the reaction were established by nmr measurements.