THE REACTIONS OF HETEROCYCLIC ISOTHIOCYANATES BEARING AN ORTHO ESTER GROUP WITH AMINOALCOHOLS

Heterocyclic isothiocyanates 1, 5, 9, bearing an o-ester group were co nverted to thiourea derivatives 2a-c, 6a-b, and 10a-b, respectively, u sing beta-aminoalcohols, and to the fused ring systems, e.g., thieno[3 ,2-d]pyrimidine 4a-b, pyrido[2,3-d]pyrimidine 8, pteridine 11a, thiazo lo[3,2-a]pyrido[2,3-d]pyrimidine 7a-b, and thiazolo[3,2-a]thieno[3,2-d ]pyrimidine 3a-c, derivatives.