MOLECULAR-CLONING AND EXPRESSION OF HUMAN CHONDROITIN 6-SULFOTRANSFERASE

Authors
FUKUTA M KOBAYASHI Y UCHIMURA K KIMATA K HABUCHI O
Citation
M. Fukuta et al., MOLECULAR-CLONING AND EXPRESSION OF HUMAN CHONDROITIN 6-SULFOTRANSFERASE, Biochimica et biophysica acta, N. Gene structure and expression, 1399(1), 1998, pp. 57-61
Citations number
18
Categorie Soggetti
Biology,Biophysics
Journal title
Biochimica et biophysica acta, N. Gene structure and expression → ACNP
ISSN journal
01674781
Volume
1399
Issue
1
Year of publication
1998
Pages
57 - 61
Database
ISI
SICI code
0167-4781(1998)1399:1<57:MAEOHC>2.0.ZU;2-P
Abstract
Using cDNA of chick chondroitin 6-sulfotransferase (C6ST), human C6ST cDNA has been isolated. The amino acid sequence of human C6ST displaye d 74% identity to chick C6ST. The major difference in amino acid seque nce between chick C6ST and human C6ST was the presence of a unique hyd rophilic domain in human C6ST. A 7.8-kb message of C6ST was expressed ubiquitously in various human adult tissues, indicating a rather diver se function of C6ST. (C) 1998 Elsevier Science B.V. All rights reserve d.