ANTIVIRAL ACTIVITY IN-VITRO OF CUPRESSUS SEMPERVIRENS ON 2 HUMAN RETROVIRUSES HIV AND HTLV

Authors
AMOUROUX P JEAN D LAMAISON JL
Citation
P. Amouroux et al., ANTIVIRAL ACTIVITY IN-VITRO OF CUPRESSUS SEMPERVIRENS ON 2 HUMAN RETROVIRUSES HIV AND HTLV, PTR. Phytotherapy research, 12(5), 1998, pp. 367-368
Citations number
10
Categorie Soggetti
Chemistry Medicinal","Pharmacology & Pharmacy
Journal title
PTR. Phytotherapy research → ACNP
ISSN journal
0951418X
Volume
12
Issue
5
Year of publication
1998
Pages
367 - 368
Database
ISI
SICI code
0951-418X(1998)12:5<367:AAIOCS>2.0.ZU;2-5
Abstract
A proanthocyanidin polymer fraction (MW 1500-2000 daltons) from Cupres sus sempervirens L. (Cupressaceae) exhibited true antiviral activity i n vitro against two retroviruses, HIV and HTLV III B. In comparison wi th AZT no toxicity was observed with PPC at concentrations of 50 mu g/ mL which exceeded the IC50 values (1.5 to 15 mu g/mL for HIV and 5 to 25 mu g/mL for HTLV). (C) 1998 John Wiley & Sons, Ltd.