Pharyngitis is one of the most common conditions treated by pediatrici
ans and primary care physicians. It occurs most commonly in school-age
children. The etiology is complex. A clinical diagnosis is difficult
to establish correctly, and it should be verified by a laboratory test
. The objectives of treatment of group A streptococcal pharyngitis are
to alleviate the symptoms and signs of acute pharyngitis, to prevent
spread of infection to others, to eradicate the bacteria from the thro
at, and to prevent suppurative and nonsuppurative sequelae. Recent stu
dies compared the clinical and bacteriologic cure rates of cefdinir, a
new oral cephalosporin antibiotic, given once or twice per day for ei
ther 5 or 10 days, with standard doses of oral penicillin given 4 time
s daily for 10 days. Cefdinir's cure rates equaled and sometimes surpa
ssed those of penicillin. Cefdinir's fewer daily doses and the possibi
lity of a shorter treatment course may improve patient compliance. Cef
dinir is a new, safe, and highly effective agent for the treatment of
group A streptococcal pharyngitis.