Chf. Hammerle et al., SUCCESSFUL BONE-FORMATION AT IMMEDIATE TRANSMUCOSAL IMPLANTS - A CLINICAL REPORT, The International journal of oral and maxillofacial implants, 13(4), 1998, pp. 522-530
The aim of this study was to test whether bone could be formed in peri
-implant defects at immediate transmucosal implants using guided bone
regeneration. Ten patients (median age 48 years) underwent comprehensi
ve dental care including the placement of an implant into an extractio
n socket immediately following removal of a tooth. An expanded polytet
rafluoroethylene membrane and the mucoperiosteal flap were adapted aro
und the neck of the implants, leaving the sites to heal in a transmuco
sal fashion. During implantation (baseline) and at membrane removal su
rgery 5 months later, the following clinical measurements from the imp
lant shoulder were assessed at six sites: implant-bone contact (defect
depth), level of the alveolar crest, level of the membrane, and dista
nce from the crest to the implant body (defect width). Estimates of th
e defect volume bordered by the membrane, the implant, and the bony wa
lls were calculated. At baseline, the mean defect depth was 4.7 mm (SD
1.3 mm, range 1 to 14 mm). At membrane removal, the mean defect depth
had decreased to 2.1 mm (SD 0.8 mm). Compared to baseline, this decre
ase was statistically significant (P <.01). The mean increase in bone
height at the deepest defect site of each implant was 6.7 mm (SD 3.0 m
m), which was significant (P <.01). At baseline, the mean value for th
e defect volume estimates was 9.45 mm(3) (SD 5.75 mm(3)). At membrane
removal, a significant decrease (P <.01) was found. After 5 months, 94
% of the area beneath the membrane was filled with new bone. It was co
ncluded that guided tissue regeneration at immediate transmucosal impl
ants is successful in generating bone into peri-implant defects.