T. Terzioglu et al., GASTROESOPHAGEAL REFLUX AND A COMPARISON OF THE DIFFERENT ANTIREFLUX PROCEDURES FOLLOWING ESOPHAGOMYOTOMY - AN EXPERIMENTAL-STUDY IN RABBITS, Surgery today, 28(8), 1998, pp. 816-821
The surgical options for achalasia remain controversial regarding the
surgical access route, whether it be transthoracic or transabdominal,
the need of, and the type of an added antireflux procedure following a
n esophagomyotomy. These questions were investigated in an experimenta
l study that used 30 albino rabbits divided into six groups, as follow
s: transabdominal Heller's esophagomyotomy (TAHE), transthoracic I-fel
ler's esophagomyotomy (TTHE), TAHE and Nissen total fundoplication (NF
), TAHE and partial fundoplication (PF), TAHE and modified fundoplicat
ion (MF), and a control group, Esophageal transit time (ETT) and gastr
oesophageal reflux (GER) were evaluated by scintigraphy on the seventh
postoperative day. When an esophagomyotomy was performed either with
a transabdominal or transthoracic approach, a significantly increased
GER rate was found in comparison to the controls. All types of antiref
lux procedures performed prevented GER effectively. Although NF and PF
groups showed a significant delay in ETT when compared to the control
group (P < 0.001), no such finding was observed in the MF group. In c
onclusion, an antireflux procedure following an esophagomyotomy is rec
ommended, A modified fundoplication was thus found to be as effective
as the other techniques in preventing GER, and was even a safer method
when obstructive findings following a total or partial fundoplication
were considered.