SUCCESSFUL TREATMENT OF CERVICAL LYMPHADENITIS CAUSED BY MYCOBACTERIAOTHER THAN TUBERCULOSIS WITH RIFABUTIN, CLARITHROMYCIN, AND PROTIONAMIDE

Citation
A. Hebestreit et al., SUCCESSFUL TREATMENT OF CERVICAL LYMPHADENITIS CAUSED BY MYCOBACTERIAOTHER THAN TUBERCULOSIS WITH RIFABUTIN, CLARITHROMYCIN, AND PROTIONAMIDE, Monatsschrift fur Kinderheilkunde, 146(7), 1998, pp. 669-672
Citations number
22
Categorie Soggetti
Pediatrics
ISSN journal
00269298
Volume
146
Issue
7
Year of publication
1998
Pages
669 - 672
Database
ISI
SICI code
0026-9298(1998)146:7<669:STOCLC>2.0.ZU;2-2
Abstract
Background: The treatment of choice of cervical lymphadenitis caused b y mycobacteria other than tuberculosis is surgical. However, a complet e cure can not be accomplished in every case. In selected cases a succ essful antimicrobial treatment has been reported. Casereport: We here report a girl aged 1 10/12 years who suffered from a cervical lymphade nitis caused by atypical mycobacteria. Three weeks following extirpati on of the affected lymphnode a new abscess developed at the site of su rgery. Since a complete surgical revision without affecting the facial nerve was impossible,the intervention was limited to incision and dra inage of the abscess. After that, a medical treatment with rifabutin, clarythromycin, and protionamide was started. During the 6 month of th erapy a complete cure could be accomplished and no severe side-effects were observed. Conclusion: In conclusion, if a surgical approach to c ure a cervical lymphadenitis caused by mycobacteria other than tubercu losis is impossible for different reasons, a drug-therapy with clarith romycin, rifabutin, and protionamide seems justified and promising. Th e value of testing the sensitivity of mycobacteria other than tubercul osis to different drugs in planing the drug-therapy is still a matter of debate.