We report the clinical features and long-term follow-up of 20 pediatri
c patients with parakeratosis pustulosa (PKP), in eight children PKP w
as considered as a clinical manifestation of psoriasis, Of these, thre
e children had skin psoriasis at the time of our observation, two deve
loped nail psoriasis, and three developed psoriatic pitting during fol
low-up, Parakeratosis pustulosa was Considered a symptom of allergic c
ontact dermatitis in four patients, whereas atopic dermatitis was poss
ibly responsible for PKP in two patients. A complete recovery from dis
ease was observed in 11 patients. The results of our study suggest tha
t PKP is not a single entity but rather represents a nail symptom that
can be produced by several inflammatory diseases, including nail psor
iasis, atopic dermatitis, and contact dermatitis.