AMIFOSTINE - A RADIOPROTECTOR IN LOCALLY ADVANCED HEAD AND NECK TUMORS

Authors
WAGNER W PROTT FJ SCHONEKAS KG
Citation
W. Wagner et al., AMIFOSTINE - A RADIOPROTECTOR IN LOCALLY ADVANCED HEAD AND NECK TUMORS, Oncology Reports, 5(5), 1998, pp. 1255-1257
Citations number
13
Categorie Soggetti
Oncology
Journal title
Oncology Reports → ACNP
ISSN journal
1021335X
Volume
5
Issue
5
Year of publication
1998
Pages
1255 - 1257
Database
ISI
SICI code
1021-335X(1998)5:5<1255:A-ARIL>2.0.ZU;2-X
Abstract
Patients with locally advanced head and neck tumors were treated +/- a mifostine (200 mg/m(2), i.v.) before radiotherapy (5x 2 Gy, for 6 week s). A significant decrease in side effects (p=0.034) using the oral as sessment score and duration of mucositis (p=0.02) in the amifostine gr oup was observed. Amifostine is feasible and effective, decreasing acu te and late side effects in patients with head and neck tumors.