T. Imaizumi et al., EXTENDED RADICAL WHIPPLE RESECTION FOR CANCER OF THE PANCREATIC HEAD - OPERATIVE PROCEDURE AND RESULTS, Digestive surgery, 15(4), 1998, pp. 299-307
Pancreatoduodenectomy is now the most fundamental operation for cancer
of the pancreatic head. However, with the conventional operative proc
edure, the resection rate is low and long-term results are extremely p
oor. We introduced an extended radical Whipple operation in 1978 to im
prove surgical curability. Systemic dissection of extended lymph nodes
and plexuses and en bloc resection of the portal vein was the basic c
oncept. The resection rate for cancer of the pancreatic head has impro
ved from 7-20 to 50%. The curative resection rate has also improved fr
om 10 to 40-50%. The extended procedure did not increase the risk of t
he Whipple operation. When curative surgery was performed, good long-t
erm survival was expected even in cases of extensive invasion to the p
ortal vein. As a result, 11 patients who underwent curative surgery ha
ve survived for a long period of time. At present, however, the majori
ty of patients are in an advanced stage at diagnosis and extended radi
cal operation plays an important role in the curative therapy for this
condition.