ENANTIOSELECTIVE DEHYDROHALOGENATION USING CHIRAL ALKOXIDES - DESIGN OF A CATALYTIC-SYSTEM ALLOWING ACCESS TO AXIALLY DISSYMMETRIC COMPOUNDS

Authors
AMADJI M VADECARD J CAHARD D DUHAMEL L DUHAMEL P PLAQUEVENT JC
Citation
M. Amadji et al., ENANTIOSELECTIVE DEHYDROHALOGENATION USING CHIRAL ALKOXIDES - DESIGN OF A CATALYTIC-SYSTEM ALLOWING ACCESS TO AXIALLY DISSYMMETRIC COMPOUNDS, Journal of organic chemistry, 63(16), 1998, pp. 5541-5546
Citations number
40
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of organic chemistry → ACNP
ISSN journal
00223263
Volume
63
Issue
16
Year of publication
1998
Pages
5541 - 5546
Database
ISI
SICI code
0022-3263(1998)63:16<5541:EDUCA->2.0.ZU;2-M
Abstract
The use of chiral alkoxides obtained from ephedrines for enantioselect ive proton abstraction is described in full. These reagents allow the practical obtention of axially dissymmetric 1,3-dioxanes via highly en antioselective dehydrohalogenation reactions. The conditions for a cat alytic use of these chiral alkoxides are defined.