ENANTIOSPECIFIC SYNTHESIS OF SUBSTITUTED BICYCLO[2.1.1]HEXANE-1-CARBOXYLIC ACIDS AND ESTERS

Authors
MARTINEZ AG VILAR ET BARCINA JO HERRERO MER CERERO SD HANACK M SUBRAMANIAN LR
Citation
Ag. Martinez et al., ENANTIOSPECIFIC SYNTHESIS OF SUBSTITUTED BICYCLO[2.1.1]HEXANE-1-CARBOXYLIC ACIDS AND ESTERS, Tetrahedron : asymmetry, 4(11), 1993, pp. 2333-2334
Citations number
8
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
4
Issue
11
Year of publication
1993
Pages
2333 - 2334
Database
ISI
SICI code
0957-4166(1993)4:11<2333:ESOSB>2.0.ZU;2-G
Abstract
The base promoted ring contraction of the readily accessible homochira l 2-oxo-1-norbornyl triflates 3 in 60% ethanol takes place with format ion of bicyclo[2.1.1]hexane (4a), (+)- or (-)-7,7-dimethyl-bicyclo[2.1 .1]hexan-1-carboxylic acids (4c or 4b) and the corresponding ethyl est ers in good yields.