As. Karaman et al., SERUM PROLACTIN LEVELS IN POSTPILL AMENORRHEIC PATIENTS, International journal of gynaecology and obstetrics, 43(2), 1993, pp. 177-180
OBJECTIVES: In this study, we evaluated the importance of the determin
ation of serum prolactin levels in postpill amenorrheic patients. METH
ODS: Serum estradiol and prolactin levels were determined in 37 postpi
ll amenorrheic patients. Bromocriptine was administered to the hyperpr
olactinemic group and clomiphene citrate to the normoprolactinemic gro
up. RESULTS: Hyperprolactinemia was observed in 21 patients (56.7%) an
d serum estradiol levels < 50 pg/ml were found in 19 of these patients
. The mean prolactin level was 71.90 +/- 23.05 ng/ml in the hyperprola
ctinemic group. While bromocriptine had a significant effect on the le
ngth of time for menstrual bleeding to return (P < 0.001), clomifene h
ad no effect. CONCLUSIONS: No treatment is required for the postpill a
menorrheic patients with normal estradiol and prolactin levels. If hyp
erprolactinemia is detected, bromocriptine may be used as a treatment
to promote normal menstrual bleeding and ovulation.