Df. Lewis et al., OBSTRUCTIVE SLEEP-APNEA DURING PREGNANCY RESULTING IN PULMONARY-HYPERTENSION, Southern medical journal (Birmingham, Ala.), 91(8), 1998, pp. 761-762
Obesity is known to increase maternal morbidity and mortality. We desc
ribe a case of obstructive sleep apnea due to obesity and discuss our
treatment of the resulting pulmonary hypertension. A patient was trans
ferred to our hospital at 29 weeks' gestation with severe anasarca and
more than a 100-pound weight gain during pregnancy, Pulmonary hyperte
nsion due to obstructive sleep apnea was diagnosed. The patient was tr
eated with nasal continuous positive airway pressure (CPAP) during sle
ep and remained in the hospital, the remainder of her pregnancy, She h
ad a massive spontaneous diuresis during her hospital stay and lost mo
re than 100 pounds. She was delivered at term via cesarean section bec
ause of transverse Lie. Preoperative hemodynamic monitoring confirmed
the diagnosis of pulmonary hypertension. This represents the first cas
e in the literature of obstructive sleep apnea leading to pulmonary hy
pertension in pregnancy. This patient responded well to nasal CPAP as
evident by the massive diuresis and good maternal outcome.