Pc. Jacob et Rp. Chand, PATHOLOGICAL LAUGHTER FOLLOWING INTRAVENOUS-SODIUM VALPROATE, Canadian journal of neurological sciences, 25(3), 1998, pp. 252-253
Background Pathological laughter can be a sign of epilepsy psychiatric
illness. effect of toxins or psychotropic drugs or of structural brai
n disease, Method: Case Studies. Result: Two patients developed inappr
opriate uncontrollable laughter following intravenous sodium valproate
for treatment of epilepsy. Conclusion: Pathological laughter can be a
side effect of intravenous sodium valproate.