HISTOLOGICAL STUDY OF COLONIC ISCHEMIA AFTER AORTIC-SURGERY

Citation
M. Welch et al., HISTOLOGICAL STUDY OF COLONIC ISCHEMIA AFTER AORTIC-SURGERY, British Journal of Surgery, 85(8), 1998, pp. 1095-1098
Citations number
33
Categorie Soggetti
Surgery
Journal title
ISSN journal
00071323
Volume
85
Issue
8
Year of publication
1998
Pages
1095 - 1098
Database
ISI
SICI code
0007-1323(1998)85:8<1095:HSOCIA>2.0.ZU;2-U
Abstract
Background Colonic ischaemia is a well documented complication of abdo minal aortic reconstruction. In this prospective study patients had ro utine preoperative and postoperative colonoscopy and biopsy, in order to determine the true incidence and implications. Methods Fifty-six pa tients undergoing elective infrarenal aortic surgery, 28 for aneurysm and 28 for occlusive disease, had colonoscopy and biopsy before and 1 week after operation. Results Colonic ischaemia was identified histolo gically in biopsies from 16 (30 per cent) of 53 patients. Almost half the patients had normal macroscopic appearances. Two factors exhibited a statistically significant association with the development of ischa emia: prolonged cross-clamp time (P < 0.05) and postoperative diarrhoe a (P < 0.001). Co-morbidity was much higher in patients with colonic i schaemia (P < 0.005). Overall morbidity was significantly greater in t he aneurysm group (P < 0.05). Conclusion Colonic ischaemia is common a fter aortic reconstruction. When suspected, colonoscopy with biopsy is diagnostic.