M. Imaizumi et al., PRIMARY CUTANEOUS T-CELL LYMPHOMA INVOLVING THE CHEEK - AN INFANT CASE WITH A UNIQUE CLINICOPATHOLOGICAL FEATURE, Leukemia & lymphoma, 31(1-2), 1998, pp. 225-229
We report a clinicopathologic feature of primary cutaneous T-cell lymp
homa (CTCL) in a five-year-old boy with increasing swelling of his che
ek since two years of age. Histologically, an infiltrate of atypical l
ymphoid cells with mature T-cell phenotype and clonality was prominent
from the dermis to the subcutaneous tissue of the cheek. Although lit
tle effect was seen with aggressive multidrug-combined chemotherapy, t
herapy with interferon-cr and steroids achieved a prolonged remission.
This patient may provide important clues to understanding the clinico
pathologic feature of rare primary CTCL in young children.