1. Blood lead measurements in samples collected from 660 London school
children during 1991 to 1992 suggest that the blood lead values in chi
ldren in the U.K. are decreasing. 2. Geometric mean values for blood l
ead were 0.18 (range 0.05-0.71) mu mol/l [3.7 (1.0-15.0) mu g/dl]. Ana
lysis of variance showed differences between ethnic groups, sex and sc
hools. An age-matched subset of 148 children was compared with 136 chi
ldren from an earlier study in 1986 and 1987. Trend analysis of the ge
ometric mean lead values showed a negative slope (b = -0.484, P < 0.00
01), with maximum values of 0.81, 1.00, 0.71 and 0.43 mu mol/l (17, 21
, 15 and 9 mu g/dl) for the years 1986, 1987, 1991 and 1992 respective
ly. 3. It is recommended that children in the U.K. being investigated
for anaemia, pica, recurrent abdominal pain or a high-risk environment
should have blood lead values measured and that the action level for
blood lead in children should be decreased from 1.19 mu mol/l to 0.48
mu mol/l (from 25 mu g/dl to 10 mu g/dl). 4. Guidance is offered to cl
inicians and other health professionals investigating excessive lead e
xposure.